Research Article
Assessment of the Impact of AI on Reducing Maternal and Infant Mortality During Epidemics in Haut-Katanga
Issue:
Volume 13, Issue 4, August 2025
Pages:
68-78
Received:
5 January 2025
Accepted:
2 February 2025
Published:
4 July 2025
Abstract: Maternal and infant mortality remain critical public health challenges in Haut-Katanga, particularly during epidemic periods that strain limited healthcare infrastructure. This study evaluates the impact of Artificial Intelligence (AI) on reducing maternal and infant mortality through a retrospective analysis using generated data from 2015 to 2023. During this period, AI adoption increased from 2% to 25%, accompanied by a decline in maternal mortality from 940 to 840 deaths per 100,000 live births, and infant mortality from 85 to 62 deaths per 1,000 live births. Linear regression analysis indicates that a 1% increase in AI adoption is associated with a reduction of approximately 1.2 maternal deaths per 100,000 and 0.15 infant deaths per 1,000, respectively. Pearson correlation analysis reveals a strong negative relationship between AI adoption and both maternal (r ≈ -0.96) and infant mortality (r ≈ -0.96), and a strong positive correlation between maternal and infant mortality (r ≈ +0.98). Additionally, trends in infectious diseases show notable declines in malaria (r = -0.84) and HIV/AIDS (r = -1.00), while measles (r = +0.83), cholera (r = +0.98), and COVID-19 (r = +0.88) increased over time. AI-based interventions, particularly in epidemic prediction and diagnostics, have contributed to measurable health gains. However, implementation remains constrained by infrastructural deficiencies, limited funding, and low digital health capacity. The findings underscore AI's emerging role in improving health outcomes and emphasize the need for strategic investments in infrastructure, workforce training, and supportive policy frameworks to enhance healthcare delivery and epidemic preparedness in resource-limited settings.
Abstract: Maternal and infant mortality remain critical public health challenges in Haut-Katanga, particularly during epidemic periods that strain limited healthcare infrastructure. This study evaluates the impact of Artificial Intelligence (AI) on reducing maternal and infant mortality through a retrospective analysis using generated data from 2015 to 2023....
Show More
Research Article
The Impact of Combined Use of Placental Extract and L-Thyroxine on Thyroid Status Parameters in Patients with Primary Hypothyroidism of Autoimmune Origin
Issue:
Volume 13, Issue 4, August 2025
Pages:
79-83
Received:
25 April 2025
Accepted:
9 July 2025
Published:
23 July 2025
DOI:
10.11648/j.ajcem.20251304.12
Downloads:
Views:
Abstract: The development of new approaches and the search for effective means for restoring thyroid function in primary hypothyroidism against the background of autoimmune damage is an urgent need. Currently, preparations made from placenta tissue and amniotic membrane are attracting attention. The placenta, as an organ that ensures the growth and development of the fetus, has in its composition active metabolites and immunosuppressive agents that ensure the preservation of pregnancy, and can have a positive effect when using such drugs in patients with autoimmune disorders. At present, the concept of a comprehensive approach to the treatment of autoimmune thyroiditis, which leads to hypothyroidism and subsequent complications using biologically active compounds, has not been finally formed. The solution to this problem will contribute to reducing the pharmacological burden on the patient with hypothyroidism and improving his quality of life. The aim of the work was to study the effect of the placenta extract preparation in combination with L thyroxine on the parameters of thyroid status in patients with primary hypothyroidism of autoimmune genesis. As part of the study, it was found that the combined use of placenta extract and L thyroxine led to a significant decrease in the level of ab-TPO already a month after therapy. After 6 and 12 months, the tendency to a gradual decrease in the content of ab-TPO was maintained. As for the functional state of the thyroid gland, the level of free fractions of thyroid hormones gradually reached the level of reference indicators. Thyroid-stimulating hormone after 12 months and 6 months after the repeated course was within the physiological norm. The use of monotherapy with L thyroxine restored the level of thyroid hormones and TSH, but the level of ab-TPO a year after the start of therapy was within the range of indicators before the start of therapy. The drug "placental extract" leads to a decrease in the tension of antithyroid immunity in patients with primary hypothyroidism at all studied periods and helps to slow down the progression of primary hypothyroidism in patients with autoimmune thyroiditis and normalize the parameters of thyroid status, which allows to reduce the daily dose of replacement therapy with levothyroxine.
Abstract: The development of new approaches and the search for effective means for restoring thyroid function in primary hypothyroidism against the background of autoimmune damage is an urgent need. Currently, preparations made from placenta tissue and amniotic membrane are attracting attention. The placenta, as an organ that ensures the growth and developme...
Show More
Research Article
Proton Beam Therapy for a Patient with Mediastinal Rhabdomyosarcoma: A Case Report
Yang Wencui*
,
Mizoe Junetsu
Issue:
Volume 13, Issue 4, August 2025
Pages:
84-90
Received:
9 June 2025
Accepted:
8 July 2025
Published:
23 July 2025
DOI:
10.11648/j.ajcem.20251304.13
Downloads:
Views:
Abstract: Rhabdomyosarcoma (RMS) is a common malignant soft tissue tumor in children and adolescents. Usually, the incidence of mediastinal RMS is extremely low. Traditional radiotherapy causes great damage to normal tissues around the tumor. Proton beams have a unique Bragg peak that can significantly reduce damage to the surrounding normal tissues while ensuring sufficient dose of the tumor. We report a case of a 33-year-old Chinese female with primary mediastinal RMS, and introduce a treatment plan involving photon radiotherapy and proton beam therapy (PBT) for this rare and interesting case. The patient started to have chest tightness and shortness of breath two months prior to presentation at the local hospital. The cardiac color ultrasound showed pericardial effusion and pericardiocentesis was performed. She was discharged after the procedure. She had a Positron Emission Tomography (PET)/ Computerized Tomography (CT) examination and the results suggested mediastinal tumor and enlarged mediastinal lymph nodes and her puncture pathology through bronchoscopy showed RMS. The following month, the patient developed chest tightness and shortness of breath again. In our hospital a multidisciplinary treatment was conducted to formulate a plan for radiotherapy of the mediastinal RMS. She received the photon and proton beam therapy. After PBT, the tumor had significantly decreased in size. PBT may improve the tumor control and the patient’s quality of life with symptomatic mediastinal RMS. The present case illustrates that PBT may be also useful for cases that are difficult to treat with photon radiotherapy and surgery.
Abstract: Rhabdomyosarcoma (RMS) is a common malignant soft tissue tumor in children and adolescents. Usually, the incidence of mediastinal RMS is extremely low. Traditional radiotherapy causes great damage to normal tissues around the tumor. Proton beams have a unique Bragg peak that can significantly reduce damage to the surrounding normal tissues while en...
Show More
