Research Article
Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder
Wenjuan Huang,
Zhonghong Wang*
Issue:
Volume 12, Issue 1, February 2024
Pages:
1-4
Received:
6 January 2024
Accepted:
19 January 2024
Published:
1 February 2024
Abstract: Objective Explore the correlation between anxiety disorder and serum 25-hydroxyvitamin D3 (25-(OH) D3) level in children, in order to guide the diagnosis and treatment of childhood anxiety disorders and to supply clinical measure. Method The experimental group was 124 children with anxiety disorders attending the Child Behavior and Development Clinic of Jingzhou Maternal and Child Health Hospital from January 2020 to December 2022, as the control group was 131 children who had health checkups in the same hospital during the meantime. The differences of serum 25-(OH) D3 levels between the two groups were compared. Children with anxiety disorder were further divided into 4 age groups according to each group with 2 years (24 months) apart: 11-12 years old (32 cases), 13-14 years old (38 cases), 15-16 years old (31 cases) and larger than 16 years old (23 cases). Then, the difference of 25-hydroxyvitamin D among 16 years old group (23 cases) was compared. Results The serum 25-(OH) D3 level of the experimental group was distinctively lower than that of the control group, [(18.25±7.68) ng/ml VS (28.63±9.52) ng/ml], P<0.05, with statistical difference; The rate of vitamin D lack and insufficiency was higher than that of the control group (89.52% VS 75.57%), P<0.05, with statistical difference; According to age group grouping, the vitamin D levels in the 15-16 year old and>16 year old groups were lower than those in the 11-12 year old and 13-14 year old groups, with statistically significant differences (P<0.05). Conclusion: Vitamin D deficiency is more common in children with anxiety disorders, and is more pronounced in children older than 15 years than in younger children.
Abstract: Objective Explore the correlation between anxiety disorder and serum 25-hydroxyvitamin D3 (25-(OH) D3) level in children, in order to guide the diagnosis and treatment of childhood anxiety disorders and to supply clinical measure. Method The experimental group was 124 children with anxiety disorders attending the Child Behavior and Development Clin...
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Review Article
Comparing Olanzapine with Placebo in Patients with Anorexia Nervosa for Increasing BMI and Weight Gain
Jalal Jbara,
Hedyeh Shaabani*,
Ekaterine Cherkezishvili,
Siavash Hosseinpour Chermahini
Issue:
Volume 12, Issue 1, February 2024
Pages:
5-7
Received:
8 January 2024
Accepted:
19 January 2024
Published:
7 March 2024
Abstract: Anorexia nervosa is an eating disorder characterized by exceptionally low body weight and a feeling of disgust toward food. In addition, it causes complications for the affected person as it affects their immunity, weakens them quickly, makes them sick and malnourished. The commonly known treatment for anorexia nervosa is psychological treatment using methods such as CBT and MANTRA. With the introduction of pharmacological medications, the aim of this review is now to determine whether olanzapine is effective compared to placebo in increasing BMI and weight gain. It was found that olanzapine had a large increase in BMI compared to placebo [F (1, 20) =6.64, p=0.018] and that it significantly reduced depression and anxiety. Further studies found that olanzapine patients gained weight more quickly and reached their BMI goals more quickly than patients taking a placebo. On the other hand, a contradictory result was found, namely that there was no significant difference between olanzapine and placebo in terms of weight recovery and psychological, depressive and anxiety symptoms. It is concluded that reliance on pharmacological therapies should be minimized until new evidence emerges and that psychotherapies such as CBT and MANTRA should be relied upon primarily to increase BMI in patients with anorexia nervosa.
Abstract: Anorexia nervosa is an eating disorder characterized by exceptionally low body weight and a feeling of disgust toward food. In addition, it causes complications for the affected person as it affects their immunity, weakens them quickly, makes them sick and malnourished. The commonly known treatment for anorexia nervosa is psychological treatment us...
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