The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
Zhenhua Huang,
Qianlin Gu,
Hong Zhan,
Zhen Yang,
Yuee Chen
Issue:
Volume 8, Issue 1, January 2020
Pages:
1-5
Received:
31 January 2020
Accepted:
18 February 2020
Published:
26 February 2020
Abstract: To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.739 (0.687 to 0.791). The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 2.0% (low-risk), 5.33% (medium-risk), and 9.67% (high-risk), respectively. The GRACE score was a useful predictor to the occurrence of 30-day cardiovascular adverse events in acute chest pain patients. Patients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.
Abstract: To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collec...
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Demography and Treatment of Complex Regional Pain Syndrome Among Children
Martin Lehmann Boesen,
Anne Estmann Christensen
Issue:
Volume 8, Issue 1, January 2020
Pages:
6-9
Received:
2 March 2020
Accepted:
8 April 2020
Published:
29 April 2020
Abstract: Introduction: Complex Regional Pain syndrome (CRPS) is a rare chronic pain syndrome characterized by amplified pain and autonomic dysfunction. A systematic multidisciplinary treatment program for affected children exists at our department. This study aims to estimate the incidence of CRPS and describe the demography, symptoms and psychosocial characteristics of the patients and evaluate the treatment results. Method: A retrospective medical chart review of all patients under the age of 16 years treated for CRPS between 2004 and 2014 at Hans Christian Andersen Children Hospital. Results: A total of 29 children fulfilled the diagnostic criteria for CRPS. The mean incidence was 2,4/100.000 children per year. Most patients were girls (90%) with a median age of 11 years. A lower extremity was most often involved (86%). Time to diagnosis had a mean of 174 days. All patients reported complete disappearance or significant reduction of pain at discharge without any medication. Walking was normalized in 75% and almost 1/3 could run normally. School attendance and social life was restored. Conclusion: The typical child with CRPS is a girl of normal stature, around 11 years old, who is affected by intolerable pain in a lower extremity and has severe limitation in walking. The condition is rare with a mean incidence of 2,4/100.000 children. Attention is important in order to reduce the diagnostic delay. Our treatment program was successful as the children were in reduced pain, gaining normal physical function and out of social isolation at completion of the program.
Abstract: Introduction: Complex Regional Pain syndrome (CRPS) is a rare chronic pain syndrome characterized by amplified pain and autonomic dysfunction. A systematic multidisciplinary treatment program for affected children exists at our department. This study aims to estimate the incidence of CRPS and describe the demography, symptoms and psychosocial chara...
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